产品说明
一般描述
Ceramides with 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 17:0(2S-OH) Ceramide is a unique ceramide containing 17C long chain base fatty acid (heptadecanoic acid)-with 2′-hydroxyl group in S configuration.
生化/生理作用
Hydroxy fatty acids (hFA)-sphingolipids helps in cell signaling. They also facilitate cell differentiation and apoptosis. hFA-ceramides in epidermis helps in permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides in the cell membrane are essential for PM02734 drug to exhibit its anti-tumor activity.
包装
5 mL Amber Glass Screw Cap Vial (860818P-5mg)
基本信息
| 经验(实验)分子式 | C35H69NO4 |
| 分子量 | 567.93 |
| NACRES | NA.25 |
产品性质
| 形式 | powder |
| 包装 | pkg of 1 × 5 mg (860818P-5mg) |
| manufacturer/tradename | Avanti Polar Lipids 860818P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCC)=O)CO |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
Sigma-Aldrich
m.cnreagent.com
