产品说明
一般描述
25:0 Coenzyme A or pentacosanoyl coenzyme A is a long chain fatty acyl-CoA. Fatty acyl-CoAs is produced from de-novo fatty acid biosynthesis and the reprocessing of pre-existing fatty acids.
25:0 Coenzyme A, also known as pentacosanoyl coenzyme A, is a coenzyme derivative of pentacosanoic acid.
应用
25:0 Coenzyme A has been used as a constituent of the internal standard mixture in liquid chromatography-electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS).
25:0 Coenzyme A or pentacosanoyl Coenzyme A has been used as a substrate for 1-acylglycerol-3-phosphate-O-acyltransferase 11 (AGPAT11) enzyme. It has also been used as an internal standard to quantify fatty acyl CoA extracted from human embryonic kidney 293 cells.
生化/生理作用
Fatty acyl-CoA plays a vital role in various cellular processes including, energy metabolism, the biosynthesis and recycling of complex lipids, the posttranslational modification of proteins and the regulation of gene expression. In addition, it facilitates most of the fatty acid modification reactions. 25:0 coenzyme A might function as a precursor of sphingolipids. Alterations in the fatty acyl-CoA metabolism leads to obesity, cardiovascular disease, diabetes mellitis and cancer.
包装
5 mL Amber Glass Screw Cap Vial (870729P-5mg)
基本信息
经验(实验)分子式 | C46H93N10O17P3S |
分子量 | 1183.27 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 5 mg (870729P-5mg) |
manufacturer/tradename | Avanti Polar Lipids 870729P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+] |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich