产品说明
一般描述
Promyeloctic Leukemia Gene product (PML) is a nuclear protein with growth-suppressive properties originally identified in the context of the PML-retinoic receptor alpha (RAR alpha) fusion protein of acute promyelocytic leukemia. PML localizes within distinct nuclear structures, called nuclear bodies, which are disrupted by the expression of PML-RAR alpha.
特异性
Recognizes PML.
免疫原
6His fusion protein corresponding to mouse PML (promyelocytic leukemia protein)
应用
Research Sub Category
Transcription Factors
Detect PML also known as Promyelocytic Leukemia Protein with Anti-PML Antibody, clone 36.1-104 (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC & WB.
Research Category
Epigenetics & Nuclear Function
质量
routinely evaluated by immunoblot on RIPA lysates from mouse embryo fibroblast (MEF1) cells
目标描述
90-106 kDa
外形
Format: Purified
Protein G Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide as a preservative.
Protein G Purified
储存及稳定性
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
MEF1 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 36.1-104, monoclonal |
species reactivity | mouse |
manufacturer/tradename | Upstate® |
technique(s) | immunocytochemistry: suitable western blot: suitable |
同位素/亚型 | IgG |
NCBI登记号 | NM_033238 |
UniProt登记号 | P29590 |
运输 | dry ice |
Gene Information | human ... PML(5371) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
Sigma-Aldrich