产品说明
一般描述
Melanoma-associated antigen recognized by T cells-1 (MART-1) (also known as Melan-A) is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. It is a transmembrane protein which is hydrophobic in nature. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. The protein is also expressed in melanoma tumors. Human MART-1 is purified by proprietary chromatographic techniques.
生化/生理作用
Melanoma-associated antigen recognized by T cells-1 (MART-1) has been shown to be essential for the functioning of glycoprotein-100 (gp100).
外形
Lyophilized without additives.
重悬
Reconstitute in water to a concentration 0.1-1 mg/mL. The solution can then be further diluted to other aqueous solutions.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥90% (HPLC) ≥90% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | ~18.0 kDa |
| 包装 | pkg of 5 μg |
| 杂质 | endotoxin, tested |
| NCBI登记号 | Q16655 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MLANA(2315) |
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