Arachidonyl trifluoromethyl ketone

产品名称：

149301-79-1
Arachidonyl trifluoromethyl ketone
AACOCF₃
Arach-CF₃
1,1,1-Trifluoromethyl-6,9,12,15-heieicosatetraen-2-one

产品介绍：

产品说明

应用

Arachidonyl trifluoromethyl ketone (AACOCF3) has been used as a anandamide degradation inhibitor to study its effects in primary astrocyte cultures.

包装

5 mg in glass bottle

生化/生理作用

Arachidonyl trifluoromethyl ketone (AACOCF3) plays a role in the inhibition of 12-hydroxyeicosatetraenoic acid (12-HETE) and thromboxane B2 produced by the platelets.
Inhibits anandamide hydrolysis in vitro; inhibits phospholipase A₂.

特点和优势

This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Hygroscopic, photosensitive, air sensitive

基本信息

经验(实验)分子式	C₂₁H₃₁F₃O
分子量	356.47
MDL编号	MFCD00236427
PubChem化学物质编号	24890647
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (NMR)
形式	oil
储存条件	desiccated protect from light under inert gas
颜色	yellow
溶解性	DMSO: >5 mg/mL
储存温度	−20℃
SMILES string	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F
InChI	1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-
InChI key	PLWROONZUDKYKG-DOFZRALJSA-N
Gene Information	human ... PLA2G1B(5319)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)