产品说明
一般描述
Lysostaphin is a glycylglycine endopeptidase. It is an important antibacterial enzyme.
生化/生理作用
Lysostaphin has the ability to cleave both viable and heat-killed S. aureus cells. It is one of the major antibacterial agents for the staphylococci. Lysostaphin cleaves the cross-linking pentaglycine bridges in the cell walls of staphylococci. Thus it is considered as an antistaphylococcal therapeutic agent.
溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。 由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键,它已被发现可用于细胞裂解,并具有潜在的抗菌治疗作用。
活性最佳pH:~7.5
单位定义
One unit will reduce the turbidity (A620) of a suspension of Staphylococcus aureus cells from 0.250 to 0.125 in 10 min at pH7.5 at 37℃ in a 6.0ml reaction mixture.
基本信息
酶学委员会(EC)编号 | 3.4.24.75 ( BRENDA | IUBMB ) |
MDL编号 | MFCD00131556 |
NACRES | NA.32 |
产品性质
质量水平 | 400 |
形式 | lyophilized powder |
specific activity | ≥500 units/mg protein |
分子量 | 26,926 Da |
组成 | protein, 50-70% biuret |
包装 | pkg of (package size sold on basis of mg protein) |
运输 | wet ice |
储存温度 | −20℃ |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H334 |
预防措施声明 | P261 - P284 - P501 |
危险分类 | Resp. Sens. 1 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich