产品说明
一般描述
Methyl 2-bromo-2-butenoate(Methyl (Z)-2-bromocrotonate) yields (S)-2-bromobutanoic acid by baker′s yeast fermentation. It undergoes biotransformation catalyzed by old yellow enzyme to yield methyl (S)-2-bromobutanoate, a key intermediate for the synthesis of chiral drugs. It is a biannelating reagent which participates in double Michael-additions.
包装
5 mL in glass bottle
基本信息
| 线性分子式 | CH3CH=CBrCOOCH3 |
| 分子量 | 179.01 |
| Beilstein | 1700999 |
| EC 号 | 241-627-1 |
| MDL编号 | MFCD00042891 |
| PubChem化学物质编号 | 57647571 |
| NACRES | NA.22 |
产品性质
| 测定 | ≥95.0% (GC) |
| 折射率 | n |
| bp | 178-182 ℃ (lit.) |
| 密度 | 1.505 g/mL at 20 ℃ (lit.) |
| 储存温度 | 2-8℃ |
| SMILES string | COC(=O)C(Br)=CC |
| InChI | 1S/C5H7BrO2/c1-3-4(6)5(7)8-2/h3H,1-2H3 |
| InChI key | DMKWWKUPZZAUQL-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 145.4 °F - closed cup |
| 闪点(C) | 63 ℃ - closed cup |
| 个人防护装备 | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
Sigma-Aldrich
m.cnreagent.com
