产品说明
一般描述
The kinetic resolution of racemic 2-phenylbutyryl chloride by sterically hindered chiral secondary alcohols has been evaluated. 2-Phenylbutyryl chloride reacts with 4-methoxybenzoyl chloride catalyzed by PdBr(Ph)(PPh3)2 to yield 1-(4-methoxyphenyl)-2-phenyl-2-buten-1-one.
应用
(R)-(-)-2-phenylbutyryl chloride may be employed as chiral reagent for the determination of dopamine and dopamine-derived salsolinol and norsalsolinol in human brain by GC-MS method. Chiral (S)-(+)-2-phenylbutyryl chloride may be used as derivatization reagent for the hydroxyl groups during the GC-MS assay for the enantiomers of 1,2-propanediol, 1,3-butanediol, 1,3-pentanediol and their corresponding hydroxyacids in biological fluids.
包装
5 mL in glass bottle
基本信息
线性分子式 | C2H5CH(C6H5)COCl |
分子量 | 182.65 |
EC 号 | 253-241-0 |
MDL编号 | MFCD00018811 |
PubChem化学物质编号 | 24861697 |
NACRES | NA.22 |
产品性质
质量水平 | 100 |
测定 | 98% |
折射率 | n |
bp | 122-125 ℃/20 mmHg (lit.) |
密度 | 1.093 g/mL at 25 ℃ (lit.) |
SMILES string | CCC(C(Cl)=O)c1ccccc1 |
InChI | 1S/C10H11ClO/c1-2-9(10(11)12)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3 |
InChI key | QGXMHCMPIAYMGT-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H314 |
预防措施声明 | P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405 |
危险分类 | Skin Corr. 1B |
储存分类代码 | 8A - Combustible, corrosive hazardous materials |
WGK | WGK 3 |
闪点(F) | 208.4 °F - closed cup |
闪点(C) | 98 ℃ - closed cup |
个人防护装备 | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
Sigma-Aldrich