产品说明
一般描述
Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K2CO3-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs2CO3 in the presence of elemental S8 or Sen to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes.
包装
5, 25 mL in glass bottle
基本信息
| 线性分子式 | ClCH(CO2C2H5)2 |
| 分子量 | 194.61 |
| EC 号 | 237-913-0 |
| MDL编号 | MFCD00009140 |
| PubChem化学物质编号 | 24867397 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 100 |
| 测定 | 95% |
| 折射率 | n |
| 密度 | 1.204 g/mL at 25 ℃ (lit.) |
| SMILES string | CCOC(=O)C(Cl)C(=O)OCC |
| InChI | 1S/C7H11ClO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3 |
| InChI key | WLWCQKMQYZFTDR-UHFFFAOYSA-N |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H314 - H335 - H400 |
| 预防措施声明 | P261 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 |
| 危险分类 | Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | 235.4 °F - closed cup |
| 闪点(C) | 113 ℃ - closed cup |
| 个人防护装备 | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
Sigma-Aldrich
m.cnreagent.com
