产品说明
应用
7-Ethoxyresorufin (7-ER) is a substrate used in environmental toxicology studies to monitor ethoxyresorufin-O-deethylase catalytic activity in the EROD assay. The EROD assay monitors the induction of the xenobiotic-metabolizing enzyme cytochrome P-450 (CYP) 1A1 and is a widely used biomarker for exposure of wildlife to substances that bind the aryl hydrocarbon (Ah) receptor. It provides evidence of receptor-mediated induction of cytochrome P450-dependant monooxygenases (the CYP1A subfamily specifically) by xenobiotic chemicals.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
Dealkylase substrate for the microfluorimetric analysis of microsomal cytochrome P-450
基本信息
| 经验(实验)分子式 | C14H11NO3 |
| 分子量 | 241.24 |
| Beilstein | 225973 |
| MDL编号 | MFCD00037661 |
| PubChem化学物质编号 | 329757074 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (UV) |
| mp | 223-225 ℃ (lit.) |
| 溶解性 | DMF: soluble DMSO: soluble alcohols: soluble |
| 荧光 | λex 464 nm; λem 540 nm in methanol(lit.) λex 571 nm; λem 585 nm in dealkylase(lit.) |
| 适用性 | suitable for fluorescence |
| 储存温度 | 2-8℃ |
| SMILES string | CCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1.Fc4c(F)c(F)c(OC(=O)CNC(=O)OCC5c6ccccc6-c7ccccc57)c(F)c4F |
| InChI | 1S/C23H14F5NO4.C14H11NO3/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15;1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h1-8,15H,9-10H2,(H,29,31);3-8H,2H2,1H3 |
| InChI key | ZOSYTBPPLWBBKM-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
