产品说明
一般描述
Bis(monoacylglycerol) phosphate (BMP) is a phospholipid containing two-phosphate linked fatty acid esterified glycerol molecule. It is present in late endosome, majorly in intraluminal vesicles (ILVs) and is hydrolyzed by BMP hydrolase. BMP accounts to 15% of total organelle lipids.
应用
18:1 BMP (S,S) may be used as an external standard for calibration in ultra performance liquid chromatography-mass spectrometry (UPLC-MS) and as an internal standard in liquid chromatography - tandem mass spectrometer (LC-MS) for quantification of lipids from tissues.It may also be used in liposome preparation for dengue virus fusion studies.
生化/生理作用
Bis(monoacylglycerol)phosphate (BMP) plays a key role in cargo sorting and protein and lipid trafficking. The levels of BMP is elevated in lysosomal storage disorders (LSD) including Wolman disease, Niemann Pick disease and neuronal ceroid lipofuscinoses. It is resistant to degradation by the enzyme, acid phospholipase.
包装
5 mL Clear Glass Sealed Ampule (857135P-5mg)
5 mL Clear Glass Sealed Ampule (857135P-10mg)
基本信息
| 经验(实验)分子式 | C42H82NO10P |
| 分子量 | 792.07 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (BMP (contains 30% positional isomers), TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 10 mg (857135P-10mg) pkg of 1 × 5 mg (857135P-5mg) |
| manufacturer/tradename | Avanti Polar Lipids 857135P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | [H][C@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+] |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
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