3,4-Dihydro-α-[(2-tricyclo[3.3.1.13,7]dec-1-ylethoxy)methyl]-2(1H)-isoquinolineethanol hydrochloride

产品名称：

473268-46-1
ADDA 5 hydrochloride
3,4-Dihydro-α-[(2-tricyclo[3.3.1.13,7]dec-1-ylethoxy)methyl]-2(1H)-isoquinolineethanol hydrochloride
1-[2-(1-Adamantyl)ethoxy]-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-propanol hydrochloride

产品介绍：

产品说明

应用

ADDA 5 hydrochloride has been used as a complex IV inhibitor to study its effects on leptomeningeal derivatives of human breast and lung cancer cells.

生化/生理作用

ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) that depletes the bioenergetics reserve capacity in intact glioma cells. ADDA 5 specifically inhibits the proliferation of chemosensitive and chemoresistant glioma cells, while sparing non-cancer cells. Additionally ADDA 5 is effective against glioma stem cells.

基本信息

经验(实验)分子式	C₂₄H₃₅NO₂ · HCl
分子量	406.00

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	OC(CN1CCC(C=CC=C2)=C2C1)COCCC34C[C@H]5C[C@H](C[C@H](C5)C4)C3.[H]Cl

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable