产品说明
Amino Acid Sequence
His-His-Gln-Lys
应用
Amyloid β (Aβ) refers to peptides derived from Amyloid precursor protein that vary in length from 36-43 amino acids. Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer′s disease and neurodegeneration. HHQK is a studied as a unique target site for inhibition of amyloid fibril formation and proteoglycan binding.
基本信息
经验(实验)分子式 | C23H36N10O6 |
分子量 | 548.60 |
NACRES | NA.32 |
产品性质
测定 | ≥95% (HPLC) |
形式 | lyophilized |
组成 | Peptide Content, ≥45% |
储存条件 | protect from light |
储存温度 | −20℃ |
Sigma-Aldrich