产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.
基本信息
经验(实验)分子式 | C17H16FN3 |
分子量 | 281.33 |
MDL编号 | MFCD28580129 |
PubChem化学物质编号 | 329825755 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | , white to yellow to light brown |
溶解性 | DMSO: 20 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F |
InChI | 1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20) |
InChI key | RHAQINSYYSNKKI-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich