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位置:首页 > 品牌 > Sigma-Aldrich > 1-(2′-Chloro-5′-nitrobenzenesulfonyl)-2-methylbenzimidazole

BIM5078

1-(2′-Chloro-5′-nitrobenzenesulfonyl)-2-methylbenzimidazole

品牌
Sigma-Aldrich
CAS
337506-43-1
货号
SML0528
规格纯度
≥98% (HPLC)
参考价格
1260.64 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
337506-43-1
BIM5078
1-(2′-Chloro-5′-nitrobenzenesulfonyl)-2-methylbenzimidazole
1-[(2-Chloro-5-nitrophenyl)sulfonyl]-2-methyl-1H-benzimidazole
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

BIM5078 is a potent Hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket and modulates the expression of known HNF4a target genes. BIM5078 also inhibits insulin gene expression by disruption of E47 and PDX-1 binding to insulin promoter. BIM5078 is selectively cytotoxic to transformed cells.

特点和优势

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式C14H10ClN3O4S
分子量351.76
MDL编号MFCD01173148
PubChem化学物质编号329825533
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 10 mg/mL, clear (warmed)
储存温度2-8℃
SMILES stringCC1=NC2=CC=CC=C2N1S(C3=C(Cl)C=CC([N+]([O-])=O)=C3)(=O)=O
InChI1S/C14H10ClN3O4S/c1-9-16-12-4-2-3-5-13(12)17(9)23(21,22)14-8-10(18(19)20)6-7-11(14)15/h2-8H,1H3
InChI keyDLUVMRPVZILBOE-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3

Sigma-Aldrich

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