BLT-1

产品名称：

321673-30-7
BLT-1
33M20
2-Hexyl-1-cyclopentanone thiosemicarbazone
Block lipid transport-1
MIT 9952-53
BLT1

产品介绍：

产品说明

应用

BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux.
BLT-1 (Block lipid transport-1) has been used as an inhibitor of the SR-BI (scavenger receptor, class B, type I) mediated lipid transfer to determine if miR-223-3p export from polymorphonuclear neutrophils (PMNs) to high-density lipoproteins (HDLs) is dependent on SR-BI-mediated lipid flux. It has also been used as a SR-BI inhibitor to study the effect of HDL on osteocalcin (OCN) expression in monocyte cell lines through SR-B1.

包装

5, 25 mg in glass bottle

生化/生理作用

Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. The compound inhibits both cellular selective lipid uptake of HDL cholesteryl ether and efflux of cellular cholesterol to HDL.

基本信息

经验(实验)分子式	C₁₂H₂₃N₃S
分子量	241.40
MDL编号	MFCD00571007
PubChem化学物质编号	329825125
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	DMSO: ≥13 mg/mL
储存温度	2-8℃
SMILES string	CCCCCCC1CCC\C1=N/NC(N)=S
InChI	1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+
InChI key	OWGUSBISUVLUJF-SDNWHVSQSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable