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Cinaciguat hydrochloride

品牌
Sigma-Aldrich
CAS
646995-35-9
货号
SML1532
规格纯度
≥98% (HPLC)
参考价格
2532.84 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
646995-35-9
Cinaciguat hydrochloride
BAY582667 hydrochloride
4-[[(4-Carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]-benzoic acid hydrochloride
4-[((4-Carboxybutyl){2-[(4-phenethylbenzyl)oxy]phenethyl}amino)methyl[benzoic]acid hydrochloride
BAY 58-2667 hydrochloride
UNII-59K0Y58UAD hydrochloride
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Cinaciguat activates sGC (soluble guanylate cyclase) independently of NO. Cinaciguat binds to sGC′s NO-sensory H-NOX domain when it is heme-depleted. Also, the compound Cinaciguat protects sGC from oxidation-induced ubiquitin-triggered degradation.
Cinaciguat, also known as BAY 58-2667, is a novel activator of guanylate cyclase. It is used in the treatment of acute decompensated heart failure (ADHF). It has been reported that cinaciguat possesses cardiovascular effects.

基本信息

经验(实验)分子式C36H39NO5 · HCl
分子量602.16
MDL编号MFCD28127267
PubChem化学物质编号329825948
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to beige
溶解性DMSO: 10 mg/mL, clear
储存温度−20℃
SMILES stringOC(C(C=C1)=CC=C1CN(CCCCC(O)=O)CCC2=CC=CC=C2OCC3=CC=C(CCC4=CC=CC=C4)C=C3)=O.[H]Cl
InChI1S/C36H39NO5.ClH/c38-35(39)12-6-7-24-37(26-30-19-21-33(22-20-30)36(40)41)25-23-32-10-4-5-11-34(32)42-27-31-17-15-29(16-18-31)14-13-28-8-2-1-3-9-28;/h1-5,8-11,15-22H,6-7,12-14,23-27H2,(H,38,39)(H,40,41);1H
InChI keyLLHMBJOVHATVSP-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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