14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate, 5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate

产品名称：

470-37-1
Cinobufagin
5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate
14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate, 5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate
14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate
华蟾蜍精

产品介绍：

产品说明

生化/生理作用

Cinobufagin is a bufanolide steroid with anti-proliferative and pro-apoptotic effects as well as antinociception activity. It has been used in Chinese herbal medicine and has been shown to have clinical applications in a variety of cancers both as an anticancer agent and to reduce cancer pain. Cinobufagin was recently identified as novel expression-mimicker that exert in vitro as well as in vivo anti-AML efficacy against AML expressing mtRUNX1.

基本信息

经验(实验)分子式	C₂₆H₃₄O₆
分子量	442.54
MDL编号	MFCD00056825

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	−20℃
SMILES string	C[C@]([C@@H](C(C=C1)=COC1=O)[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@]5([H])[C@@]3(CC[C@H](O)C5)C)[C@@]64[C@@H]2O6
InChI	1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3/t16-,17+,18+,19-,21+,22-,23-,24+,25-,26-/m1/s1
InChI key	SCULJPGYOQQXTK-OLRINKBESA-N

安全信息

象形图
警示用语：	Danger
危险声明	H300 + H310 + H330
预防措施声明	P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
危险分类	Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
储存分类代码	6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable