3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis-1H-indole

产品名称：

94944-80-6
DIM-C-pPhtBu
3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis-1H-indole
1,1-Bis(3-indolyl)-1-(p-t-butylphenyl)methane

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

DIM-C-pPhtBu, similar to other C-DIMs, exhibits a broad range of anticancer and antitumorigenic activities against multiple tumor types. DIM-C-pPhtBu causes apoptotic cell death of KB cells by activation of endoplasmic reticulum stress through induction of CHOP protein that is associated with the apoptosis in human oral cancer cells. Also it appears to induce an autophagic cell death in drug-resistant ER-negative breast tumors.

基本信息

经验(实验)分子式	C₂₇H₂₆N₂
分子量	378.51
EC 号	305-658-5
MDL编号	MFCD18082348
PubChem化学物质编号	329825365
NACRES	NA.77

产品性质

质量水平	100
测定	≥96% (HPLC)
形式	powder
储存条件	desiccated
颜色	light orange to dark orange
溶解性	DMSO: >15 mg/mL
储存温度	−20℃
SMILES string	CC(C)(C)c1ccc(cc1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45
InChI	1S/C27H26N2/c1-27(2,3)19-14-12-18(13-15-19)26(22-16-28-24-10-6-4-8-20(22)24)23-17-29-25-11-7-5-9-21(23)25/h4-17,26,28-29H,1-3H3
InChI key	NCPVEZRBHNDCIV-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable