EMI1

产品名称：

35773-42-3
EMI1
3-(1,3-benzoxazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
3-(Benzoxazol-2-yl)-7-diethylamino-2H-benzopyran-2-one
3-(2-Benzoxazolyl)-7-(diethylamino)coumarin

产品介绍：

产品说明

生化/生理作用

EMI1 (ChemBridge 5213777) is a call penetrant and potent inhibitor of EGFR signaling in EGFR L858R/T790M/C797S and ex19del/T790M/C797S triple mutants associated with drug-resistant NSCLC. Additionally, EMI1 potently depolymerized interphase microtubules, disrupts spindle formation and induced mitotic block in PC9 EGFR ex19del/T790M/C797S cells. EMI1 exhibits potent anti-proliferative activity against various cancer cell lines.

基本信息

经验(实验)分子式	C₂₀H₁₈N₂O₃
分子量	334.37
MDL编号	MFCD00489515

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable