(αR)-α-Cyclopentyl-α-hydroxy-N-[1-(4-methyl-3-penten-1-yl)-4-piperidinyl]-Benzeneacetamide fumarate

产品名称：

257603-40-0
J104129 fumarate
J-104129
(αR)-α-Cyclopentyl-α-hydroxy-N-[1-(4-methyl-3-penten-1-yl)-4-piperidinyl]-Benzeneacetamide fumarate

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

J104129 is a muscarinic M3 receptor antagonist greater than 100-fold selectivity for M3 over M2 receptors. Its Ki for M3 receptors = 4.2 nM compared to a Ki of 490 nM for M2 receptors. J-104129 showed potent bronchodilator activity in animal studies.

基本信息

经验(实验)分子式	C₂₄H₃₆N₂O₂ · C₄H₄O₄
分子量	500.63
MDL编号	MFCD09753272

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -6 to -8°, c = 1 in methanol
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C(O)/C=C/C(O)=O.CC(C)=CCCN(CC1)CCC1NC([C@](C2CCCC2)(O)C3=CC=CC=C3)=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable