Longdaysin

产品名称：

Longdaysin
9-isopropyl-N-(3-(trifluoromethyl)benzyl)-9H-purin-6-amine

产品介绍：

产品说明

应用

Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior.

包装

5, 25 mg in glass bottle

生化/生理作用

Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.

基本信息

经验(实验)分子式	C₁₆H₁₆F₃N₅
分子量	335.33
MDL编号	MFCD20527323
PubChem化学物质编号	329825177

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	DMSO: ≥15 mg/mL
储存温度	2-8℃
SMILES string	CC(C)N(C=N1)C2=C1C(NCC3=CC(C(F)(F)F)=CC=C3)=NC=N2
InChI	1S/C16H16F3N5/c1-10(2)24-9-23-13-14(21-8-22-15(13)24)20-7-11-4-3-5-12(6-11)16(17,18)19/h3-6,8-10H,7H2,1-2H3,(H,20,21,22)
InChI key	REKSFCCYDQMSIN-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H315 - H319 - H335 - H361d
预防措施声明	P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable