ML402

产品名称：

298684-44-3
ML402
N-[2-(4-Chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide
N-[2-(4-Chloro-2-methylphenoxy)ethyl]-2-thiophenecarboxamide

产品介绍：

产品说明

生化/生理作用

ML402 is a selective activator of K2P2.1 (TREK-1) and K2P10.1 (TREK-2) potassium channels. It was used to determine a cryptic selectivity filter binding site of the K2P2.1 (TREK-1) channel, designated the K2P modulator pocket. This binding pocket stabilizes an active "leak-mode" conformation, binding small-molecule activators that restrict the mobility of the selectivity filter and surrounding structure.

基本信息

经验(实验)分子式	C₁₄H₁₄ClNO₂S
分子量	295.78
MDL编号	MFCD01990273

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	−20℃
SMILES string	ClC1=CC=C(OCCNC(C2=CC=CS2)=O)C(C)=C1

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable