产品说明
应用
MRS 1754 hydrate has been used as an adenosine receptor A2B (RA2B) antagonist:
包装
5, 25 mg in glass bottle
生化/生理作用
MRS 1754 hydrate is a p-cyanoanilide xanthine derivative. It might act as a potential anti-asthmatic drug.
MRS 1754 hydrate is a potent A2B adenosine receptor antagonist.
特点和优势
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
法律信息
Manufactured and sold under license from Adenosine Therapeutics LLC.
基本信息
经验(实验)分子式 | C26H26N6O4 · xH2O |
分子量 | 486.52 (anhydrous basis) |
MDL编号 | MFCD11046004 |
PubChem化学物质编号 | 24278793 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
颜色 | off-white |
溶解性 | DMSO: soluble >10 mg/mL |
储存温度 | room temp |
SMILES string | O.CCCN1C(=O)N(CCC)c2[nH]c(nc2C1=O)-c3ccc(OCC(=O)Nc4ccc(cc4)C#N)cc3 |
InChI | 1S/C26H26N6O4.H2O/c1-3-13-31-24-22(25(34)32(14-4-2)26(31)35)29-23(30-24)18-7-11-20(12-8-18)36-16-21(33)28-19-9-5-17(15-27)6-10-19;/h5-12H,3-4,13-14,16H2,1-2H3,(H,28,33)(H,29,30);1H2 |
InChI key | ZACJDWOPQROWIK-UHFFFAOYSA-N |
Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140) rat ... Adora1(29290), Adora2a(25369), Adora2b(29316) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich