PF-04363467 hydrochloride

产品名称：

2040055-81-8
PF-04363467 hydrochloride
N-[4-[(2S)-4-Ethyl-2-morpholinyl]-2-methylphenyl]-4-(1-methylethyl)-benzenesulfonamide hydrochloride
(S)-N-[4-(4-Ethyl-2-morpholinyl)-2-methylphenyl]-4-(1-methylethyl)benzenesulfonamide hydrochloride
PF-4363467 hydrochloride

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

PF-4363467 hydrochloride is a Dopamine D3/D2 receptor antagonist. PF-4363467 has 100-fold selectivity for D3 with a Ki value of 3.1 nM for D3R compared to a Ki value of 692 nM for D2R and high selectivity for D3R compared to other biogenic amine receptors. PF-4363467 attenuated opioid drug-seeking behavior in a rat model of addiction without causing the extrapyramidal symptoms often associated with D2R antagonism.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₂H₃₀N₂O₃S · HCl
分子量	439.01
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	white to beige
溶解性	H₂O: 3 mg/mL, clear (warmed)
创始人	Pfizer
储存温度	room temp
SMILES string	[H]Cl.CC1=CC([C@H]2CN(CC)CCO2)=CC=C1NS(C3=CC=C(C(C)C)C=C3)(=O)=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable