Qc1

产品名称：

403718-45-6
Qc1
1,2,3,4-Tetrahydro-4-oxo-N-(phenylmethyl)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-7-quinazolinecarboxamide

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Qc1 is a reversible inhibitor of threonine dehydroxygenase (TDH). The IC₅₀ value for inhibition of TDH by Qc1 is 500 nM, with no detectable inhibition of other dehydroxygenase enzymes at concentrations up to 10 mM. Qc1 induces arrest and autophagy of mouse ES cells with an EC₅₀ of 3 mM.

基本信息

经验(实验)分子式	C₂₃H₁₆F₃N₃O₂S
分子量	455.45
MDL编号	MFCD02649259
PubChem化学物质编号	329825432
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 5 mg/mL (clear solution, warmed)
储存温度	2-8℃
SMILES string	FC(F)(F)c1cccc(c1)N2C(=S)Nc3cc(ccc3C2=O)C(=O)NCc4ccccc4
InChI	1S/C23H16F3N3O2S/c24-23(25,26)16-7-4-8-17(12-16)29-21(31)18-10-9-15(11-19(18)28-22(29)32)20(30)27-13-14-5-2-1-3-6-14/h1-12H,13H2,(H,27,30)(H,28,32)
InChI key	IFNVTSPDMUUAFY-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable