Ribocil-C

产品名称：

1825355-56-3
Ribocil-C
2-[(3S)-1-[[1-(2-Pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)-4(3H)-pyrimidinone

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches. Riboswitches are cis regulatory elements present in non-coding RNA that specifically bind to natural ligands to regulate gene expression. Ribocil-C blocks the flavin mononucleotide riboswitch-mediated expression of the ribB gene, which is required for riboflavin biosynthesis, with an IC₅₀ value of 23 nM. Ribocil-C inhibited bacterial cell growth of E. coli MB5746 and bacterial burden in a mouse E. coli septicaemia model of infection.

基本信息

经验(实验)分子式	C₂₁H₂₁N₇OS
分子量	419.50
MDL编号	MFCD29472282
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C1NC([C@@]2([H])CCCN(CC3=CN(C4=NC=CC=N4)C=N3)C2)=NC(C5=CC=CS5)=C1

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable