Toceranib

产品名称：

356068-94-5
Toceranib
SU11654
5-[(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(pyrrolidin-1-yl)ethyl]-1H-pyrrole-3-carboxamide
PHA-291639
SU-11654

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Toceranib (SU11654) is a protein tyrosine kinase inhibitor that selectively targets stem cell factor receptor c-kit, including all forms of mutant Kit, as well as PDGFR and VEGFR. Toceranib exhibited Ki values of 5 nM for PDGFR and 6 nM for VEGFR. Toceranib phosphate is approved for use in mast cell cancer in dogs.

其他说明

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₂H₂₅FN₄O₂
分子量	396.46

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	yellow to orange
溶解性	DMSO: 2 mg/mL, clear (warmed)
创始人	Pfizer
储存温度	room temp

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319
预防措施声明	P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable