产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
YM-298198 is an orally active, noncompetitive mGlu1 receptor antagonist. The compound inhibits glutamate-induced inositol phosphate production in NIH3T3 cells (IC50 = 16 nM). YM-298198 displays analgesic and antinociceptive properties in vivo.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C18H22N4OS · HCl |
分子量 | 378.92 |
MDL编号 | MFCD08703122 |
PubChem化学物质编号 | 329825561 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | desiccated |
颜色 | white to beige |
溶解性 | H2O: 5 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | Cl.CN(C1CCCCC1)C(=O)c2sc3nc4ccc(N)cc4n3c2C |
InChI | 1S/C18H22N4OS.ClH/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18;/h8-10,13H,3-7,19H2,1-2H3;1H |
InChI key | WYTJVUVCSUWZTH-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich