产品说明
生化/生理作用
AM-9074 is a potent activator of glucokinase, which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-9074 had an EC50 value of 160 nM with good solubility, oral bioavailability and acceptable clearance in rodents, and was shown to lower plasma glucose levels.
基本信息
经验(实验)分子式 | C18H22N4O4 |
分子量 | 358.39 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | CNC(NC1=CC(OC2=CC(OC)=CN=C2)=C([C@H]3CCCOC3)C=N1)=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |