产品说明
一般描述
AM6545 is a cannabinoid (CB1) receptor antagonist.
包装
5, 25 mg in glass bottle
生化/生理作用
AM6545 helps in decreasing the development of albuminuria, inflammation and expression of markers of fibrosis. It also helps in the down-regulation of nephrin and podocin. It has the ability to repress the ingestion of food and food-reinforced behaviour.
AM6545 is a peripheral CB1 cannabinoid receptor antagonist and appetite suppressant.
特点和优势
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C26H23Cl2N5O3S |
| 分子量 | 556.46 |
| MDL编号 | MFCD19053178 |
| PubChem化学物质编号 | 329770727 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to off-white |
| 溶解性 | DMSO: >25 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(cc3)C#CCCC#N)C(=O)NN4CCS(=O)(=O)CC4 |
| InChI | 1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34) |
| InChI key | XBHQLFVDGLPBCK-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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