CGP52432

产品名称：

139667-74-6
CGP52432
[3-[[(3,4-Dichlorophenyl)methyl]amino]propyl](diethoxymethyl)-phosphinic acid

产品介绍：

产品说明

应用

CGP52432 has been used as a γ-aminobutyric acid B (GABA_B) antagonist:

to study its effects on the simulation of the onset of status epilepticus (SE) in mice
for voltage-clamp recording in mice neurons
to study its effects on the GABA_B receptor-mediated neurotransmission in guinea pig hippocampus

包装

5, 25 mg in glass bottle

生化/生理作用

CGP52432 participates in inhibiting the glycine overflow in the hippocampus.
CGP52432 is a very potent antagonist of GABA_B receptors. (IC₅₀ = 85 nM).

特点和优势

This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

注意：不要冻存。

基本信息

经验(实验)分子式	C₁₅H₂₄Cl₂NO₄P
分子量	384.24
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 1 mg/mL, clear (warmed)
储存温度	2-8℃
InChI	1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
InChI key	GJZVQXWEIYRHBE-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable