(E)-3-ethyl-2-methyl-3-(2′′,4′′,5′′-trimethoxy)phenyl-1-(2′,4′,5′-trimethoxy)phenyl-1-propene

产品名称：

80423-94-5
Diasarone-I
1,1′-[(1E)-3-Ethyl-2-methyl-1-propene-1,3-diyl]bis[2,4,5-trimethoxybenzene]
Diasarone 1
(E)-3-ethyl-2-methyl-3-(2′′,4′′,5′′-trimethoxy)phenyl-1-(2′,4′,5′-trimethoxy)phenyl-1-propene
NEOLASA-I
Diasarone I

产品介绍：

产品说明

生化/生理作用

The antiviral effect of Diasarone-I includes half maximal effective concentration (EC₅₀) of 4.5 μM and half maximal cytotoxicity concentration (CC₅₀) of >80 μM.
Diasarone-I is an antiviral agent isolated form Acorus tatarinowii Schott that potently inhibits dengue viral infection. Diasarone-I is binds to the viral 2′O methyltransferase of nonstructural protein 5 (NS5). It also decreases the DENV2-induced STAT1 phosphorylation and IFN-stimulated genes (ISGs) expression.

基本信息

经验(实验)分子式	C₂₄H₃₂O₆
分子量	416.51

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	−20℃
SMILES string	C/C(C(CC)C1=CC(OC)=C(OC)C=C1OC)=C\C2=C(OC)C=C(OC)C(OC)=C2

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable