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Isavuconazonium sulfate

品牌
Sigma-Aldrich
CAS
946075-13-4
货号
SML3188
规格纯度
≥95% (HPLC)
参考价格
780.67 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
946075-13-4
Isavuconazonium sulfate
(2-{[(1-{1-[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1H-1,2,4-triazol-4-ium-4-yl}ethoxy)carbonyl](methyl)amino}pyridin-3-yl)methyl N-methylglycinate hydrogen sulfate
BAL8557
BAL 8557-002
产品介绍:

产品说明

生化/生理作用

Isavuconazonium sulfate (BAL8557) is a prodrug of isavuconazole (BAL 4815), a triazole antifungal drug. Isavuconazole inhibits fungal sterol biosynthesis by inhibition of cytochrome P450 sterol 14-α-demethylase (CYP51), an enzyme in the sterol biosynthesis pathway that leads from lanosterol to ergosterol. Isavuconazonium sulfate has been approved for the treatment of both invasive aspergillosis and invasive mucormycosis.

基本信息

经验(实验)分子式C35H35F2N8O5S · SO4H
分子量814.84
MDL编号MFCD27987905

产品性质

质量水平100
测定≥95% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃
SMILES stringO=S(O)([O-])=O.N#CC(C=C1)=CC=C1C2=CSC([C@H](C)[C@](O)(CN3C=[N+](C(C)OC(N(C)C4=NC=CC=C4COC(CNC)=O)=O)C=N3)C5=CC(F)=CC=C5F)=N2

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H361d - H372 - H410
预防措施声明P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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