产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Kurarinone, a flavanone from Sophora flavescens roots, is a potent activator of the large-conductance calcium-activated potassium channel (BKCa channel). Kurarinone exhibits strong preference to potentiate the homomeric BKCa channel composed only of the α subunits. Kurarinone reduces acetylcholine induced contraction of rat urinary bladder strips and decreased the voiding frequency in a rat OAB model. Kurarinone exhibits cytotoxic and antiinflamatory activity. Kurarinone sensitizes TRAIL-induced tumor cell apoptosis via suppression of NF-
基本信息
经验(实验)分子式 | C26H30O6 |
分子量 | 438.51 |
产品性质
质量水平 | 100 |
生物来源 | (isolated from Caragana sinica) |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | protect from light |
颜色 | white to beige |
溶解性 | DMSO: 20 mg/mL, clear |
储存温度 | −20℃ |
SMILES string | CC([C@H](CC=C(C)C)CC1=C2C(C(C[C@@H](C3=CC=C(O)C=C3O)O2)=O)=C(OC)C=C1O)=C |
InChI | 1S/C25H28O6/c1-13(2)5-6-15(14(3)4)9-18-20(28)11-21(29)24-22(30)12-23(31-25(18)24)17-8-7-16(26)10-19(17)27/h5,7-8,10-11,15,23,26-29H,3,6,9,12H2,1-2,4H3 |
InChI key | XRYVAQQLDYTHCL-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |