LY2584702 tosylate

产品名称：

1082949-68-5
LY2584702 tosylate
LY 2779964
4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine, 4-methylbenzenesulfonate (1:1)
LY-2584702 tosylate
LY2779964
LYS6K2 tosylate
LY-2779964
LY 2584702 tosylate

产品介绍：

产品说明

生化/生理作用

LY2584702 is an orally active, ATP-competitive, potent and selective ribosomal protein S6 kinase (p70 S6 kinase, p70S6K, S6K1) inhibitor (IC₅₀ = 4 nM; selective over 83 other kinases and 45 cell surface markers). LY2584702 inhibits HCT116 cellular S6 phosphorylation (IC₅₀ 0.1-0.24 μM) and shows anti-tumor efficacy in U87MG glioblastoma and HCT116 colon carcinoma xenograft models in vivo (2.5 mg/kg bid. po.).

基本信息

经验(实验)分子式	C₂₁H₁₉F₄N₇ · C₇H₈O₃S
分子量	617.62
MDL编号	MFCD29054739

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable