NNGH

产品名称：

161314-17-6
NNGH
BML-205
N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3,stromelysin 1, progelatinase). NNGH has been used to inhibit MMP-3 in a variety of studies. Inhibition of MMP-3 with NNGH significantly suppressed the expression of iNOS and pro-inflammatory cytokines and the activities of NF-KB, AP-1, and MAPK in LPS-stimulated microglia, suggesting a role for MMP-3 in neuroinflammation.

基本信息

经验(实验)分子式	C₁₃H₂₀N₂O₅S
分子量	316.37
MDL编号	MFCD02179370
PubChem化学物质编号	329825565

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 15 mg/mL, clear
储存温度	2-8℃
SMILES string	COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO
InChI	1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
InChI key	JIRXORZYIXSWOB-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable