Nodinitib-1

产品名称：

799264-47-4
Nodinitib-1
1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine
CID-1088438
ML130

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.

基本信息

经验(实验)分子式	C₁₄H₁₃N₃O₂S
分子量	287.34
MDL编号	MFCD04322367
PubChem化学物质编号	329825379
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: >10 mg/mL
储存温度	2-8℃
SMILES string	NC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2
InChI	1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
InChI key	SRFABRWQVPCPRG-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable