产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.
基本信息
经验(实验)分子式 | C14H13N3O2S |
分子量 | 287.34 |
MDL编号 | MFCD04322367 |
PubChem化学物质编号 | 329825379 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: >10 mg/mL |
储存温度 | 2-8℃ |
SMILES string | NC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2 |
InChI | 1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16) |
InChI key | SRFABRWQVPCPRG-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich