PB28 dihydrochloride

产品名称：

172906-90-0
PB28 dihydrochloride
1-Cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine dihydrochloride

产品介绍：

产品说明

应用

PB28 dihydrochloride has been used to test its inhibitory effect on potassium voltage-gated channel, shab-related subfamily, member 1, Kv2.1.

生化/生理作用

PB28, a cyclohexylpiperazine derivative, is a sigma 1 (σ1)-R antagonist. It elicits anti-tumor activity in breast, ovarian and colorectal cancer cell lines.
Selective σ₂opioid receptor ligand; putative σ₂ agonist

基本信息

线性分子式	C₂₄H₄₀Cl₂N₂O
分子量	443.49
MDL编号	MFCD06798349
PubChem化学物质编号	329820345
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
储存条件	desiccated
颜色	white
溶解性	H₂O: ~10 mg/mL at 60 ℃
SMILES string	Cl[H].Cl[H].COc1cccc2C(CCCN3CCN(CC3)C4CCCCC4)CCCc12
InChI	1S/C24H38N2O.2ClH/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21;;/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3;2*1H
InChI key	DSRBJOQIBXACIV-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves