产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production from transcripts containing nonsense mutations-generated PTCs, including ataxia-telangiectasia (A-T) mutated in A-T lymphoblastoid cell cultures and dystrophin in mdx Duchenne muscular dystrophy (DMD) mice-derived muscle myotubes.
基本信息
经验(实验)分子式 | C14H9N3O4S |
分子量 | 315.30 |
MDL编号 | MFCD00808624 |
PubChem化学物质编号 | 329826040 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | yellow to orange |
溶解性 | DMSO: 20 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | O=C1NC(S/C1=C\C2=CC=C(C3=C([N+]([O-])=O)C=CC=C3)O2)=N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
预防措施声明 | P301 + P312 + P330 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich