产品说明
生化/生理作用
SGC-CAMKK2-1 (YL-36) is a potent and selective CaM kinase kinase (CaMKK) inhibitor (CAMKK2 IC50 = 30 nM) that inhibits C4-2 cellular AMPK phosphorylation (IC50 = 1.6 μM) with selective affinity toward CAMKK1/2 over other kinases (404-kinase panel kinome-wide Discoverx screen).
基本信息
经验(实验)分子式 | C26H23NO3 |
分子量 | 397.47 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | CC1=CC(C2=CN=C(OC=C3C4=CC(C5CCCC5)=C(C(O)=O)C=C4)C3=C2)=CC=C1 |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich