SMER3

产品名称：

67200-34-4
SMER3
9H-Indeno-[1,2-e]-[1,2,5]-oxadiazolo-[3,4-b]-pyrazin-9-one

产品介绍：

产品说明

应用

SMER3 may be used in cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

Inhibition of SCF^Met30 by SMER3 blocks the ubiquitination of Met4 and activates the Met4-containing transcription complex. The induction of MET-genes results in cell cycle arrest and reduced cell proliferation.¹
Small molecule enhancer of rapamycin (SMER); specific inhibitor of Ubiquitin E3 ligase.

基本信息

经验(实验)分子式	C₁₁H₄N₄O₂
分子量	224.18
MDL编号	MFCD00451458
PubChem化学物质编号	329824591
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	yellow
溶解性	DMSO: ≥30 mg/mL
储存温度	2-8℃
SMILES string	O=C1c2ccccc2-c3nc4nonc4nc13
InChI	1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
InChI key	SFSSAKVWCKFRHE-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable