产品说明
生化/生理作用
UNC2170 is an inhibitor of DNA damage response protein 53BP1, which recognizes dimthyl lysine residues on lysine 20 on histone H4 that is involved in double-strand DNA breaks. 17-fold selectivity for 53BP1 as compared to other methyl-lysine (Kme) binding proteins tested.
基本信息
经验(实验)分子式 | C14H21BrN2O · C2HF3O2 |
分子量 | 427.26 |
PubChem化学物质编号 | 329825874 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | oil |
颜色 | colorless to yellow |
储存温度 | 2-8℃ |
SMILES string | BrC1=CC=CC(C(NCCCNC(C)(C)C)=O)=C1.FC(F)(C(O)=O)F |
InChI | 1S/C14H21BrN2O.C2HF3O2/c1-14(2,3)17-9-5-8-16-13(18)11-6-4-7-12(15)10-11;3-2(4,5)1(6)7/h4,6-7,10,17H,5,8-9H2,1-3H3,(H,16,18);(H,6,7) |
InChI key | DPAGQICQYYQSQP-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P301 + P310 + P330 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich