W-13

产品名称：

88519-57-7
W-13
W13
N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells.
W-13 is a membrane-permeable calmodulin antagonist. W-13 inhibits Ca²⁺-calmodulin-dependent phosphodiesterase and has been shown to inhibit the EGF-dependent activation of EGFR in N7xHERc fibroblasts.

特点和优势

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式	C₁₄H₁₇ClN₂O₂S · HCl
分子量	349.28
MDL编号	MFCD00058030
PubChem化学物质编号	329825589
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 20 mg/mL, clear
储存温度	room temp
SMILES string	Cl.NCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12
InChI	1S/C14H17ClN2O2S.ClH/c15-13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)17-10-2-1-9-16;/h3-8,17H,1-2,9-10,16H2;1H
InChI key	IKMXJMNRHREPOD-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable