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X80

品牌
Sigma-Aldrich
CAS
292065-64-6
货号
X3629
规格纯度
≥98% (HPLC)
参考价格
1515.08 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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产品名称:
292065-64-6
X80
5-(5-{[1-(3-carboxyphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}-2-furyl)-2-chlorobenzoic acid
产品介绍:

产品说明

应用

X80 has been used as an inhibitor of nucleotide excision repair (NER) pathway to study its effects on 8-hydroxy-2′-deoxyguanosine (8-OHdG) excision in the zygote post-fertilization.

包装

5, 25 mg in glass bottle

生化/生理作用

X80 is an inhibitor of xeroderma pigmentosum group A protein (XPA protein) required for the removal of all types of DNA lesions repaired by nucleotide excision repair Including both transcription coupled and global genomic nucleotide excision repair.

基本信息

经验(实验)分子式C23H15ClN2O6
分子量450.83
MDL编号MFCD02086439
PubChem化学物质编号329830804
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 orange
溶解性DMSO: >40 mg/mL
储存温度2-8℃
SMILES stringCC1=NN(c2cccc(c2)C(O)=O)C(=O)\C1=C/c3ccc(o3)-c4ccc(Cl)c(c4)C(O)=O
InChI1S/C23H15ClN2O6/c1-12-17(21(27)26(25-12)15-4-2-3-14(9-15)22(28)29)11-16-6-8-20(32-16)13-5-7-19(24)18(10-13)23(30)31/h2-11H,1H3,(H,28,29)(H,30,31)/b17-11-
InChI keyXZRBYOCWWJMJRZ-BOPFTXTBSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H413
预防措施声明P273 - P301 + P312 + P330
危险分类Acute Tox. 4 Oral - Aquatic Chronic 4
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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