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位置:首页 > 品牌 > Sigma-Aldrich > YM-202074 倍半富马酸盐 水合物

YM-202074 sesquifumarate salt hydrate

YM-202074 倍半富马酸盐 水合物

品牌
Sigma-Aldrich
CAS
299900-84-8
货号
Y1271
规格纯度
≥98% (HPLC)
参考价格
1318.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
299900-84-8
YM-202074 sesquifumarate salt hydrate
YM 202074
YM202074
N-cyclohexyl-6-{[(2-methoxyethyl)(methyl)amino]methyl}-N-methylthiazolo[3,2-a]benzimidazole-2-carboxamide
YM-202074 倍半富马酸盐 水合物
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

YM-202074 is a potent and selective allosteric metabotropic glutamate receptor type 1 (mGluR1) antagonist. It bound an allosteric site of rat mGluR1 with a Ki value of 4.8 nM. It also inhibited the mGluR1-mediated inositol phosphates production in rat cerebellar granule cells with an IC50 value of 8.6 nM, while showing selectivity over mGluR(2-7).

基本信息

经验(实验)分子式C22H30N4O2S · 1.5C4H4O4 · xH2O
分子量588.67 (anhydrous basis)
MDL编号MFCD16879020
PubChem化学物质编号329831586
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to off-white
溶解性DMSO: >20 mg/mL
H2O: >5 mg/mL
储存温度room temp
SMILES stringO.OC(=O)\C=C\C(O)=O.OC(=O)\C=C\C(O)=O.COCCN(C)Cc1ccc2nc3sc(cn3c2c1)C(=O)N(C)C4CCCCC4.COCCN(C)Cc5ccc6nc7sc(cn7c6c5)C(=O)N(C)C8CCCCC8.COCCN(C)Cc9ccc%10nc%11sc(cn%11c%10c9)C(=O)N(C)C%12CCCCC%12
InChI1S/3C22H30N4O2S.2C4H4O4.H2O/c3*1-24(11-12-28-3)14-16-9-10-18-19(13-16)26-15-20(29-22(26)23-18)21(27)25(2)17-7-5-4-6-8-17;2*5-3(6)1-2-4(7)8;/h3*9-10,13,15,17H,4-8,11-12,14H2,1-3H3;2*1-2H,(H,5,6)(H,7,8);1H2/b;;;2*2-1+;
InChI keyMCGFIZFYSARKON-RAMYONIISA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H319
预防措施声明P301 + P310 + P330 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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