产品说明
一般描述
A cell-permeable, thiazolidinone compound that specifically inhibits c-Myc-Max interaction, thereby preventing the transactivation of c-Myc targeted gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (Effective concentration: 64 µM using c-Myc-transfected Rat1a fibroblasts).
A cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).
包装
10 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
c-Myc
警告
Toxicity: Carcinogenic / Teratogenic (D)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Yin, X., et al. 2003. Oncogene22, 6151.
法律信息
Sold under license of U.S. Patent 7,026,343.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C12H11NOS2 |
| 分子量 | 249.35 |
| MDL编号 | MFCD00758517 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (sum of two isomers, HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | yellow |
| 溶解性 | DMSO: 200 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H317 - H319 |
| 预防措施声明 | P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Sens. 1 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
