产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder, binding within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom without zinc chelation.
特点和优势
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式 | C17H22N2O3 |
分子量 | 302.37 |
MDL编号 | MFCD12828877 |
PubChem化学物质编号 | 329775209 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to off-white |
溶解性 | DMSO: >10 mg/mL |
创始人 | Wyeth |
储存温度 | 2-8℃ |
SMILES string | O=C(NCCCCN1CCOCC1)c2cc3ccccc3o2 |
InChI | 1S/C17H22N2O3/c20-17(16-13-14-5-1-2-6-15(14)22-16)18-7-3-4-8-19-9-11-21-12-10-19/h1-2,5-6,13H,3-4,7-12H2,(H,18,20) |
InChI key | KUJQEQAVMNFFAO-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich