产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
NCTT-956 is a very potent, specific inhibitor of 12-lipoxygenase (12-LO) activity, with an IC50 of 800 nM, no activity against 5-LO and greater than 25-fold selectivity over 15-LO. Specific inhibition of 12-LO by NCTT-956 in platelets blocks PKC activation, aggregation, granule secretion and αIIbB3 activation.
基本信息
| 经验(实验)分子式 | C17H15N3O4S |
| 分子量 | 357.38 |
| MDL编号 | MFCD02228855 |
| PubChem化学物质编号 | 329825448 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (NMR) |
| 形式 | powder |
| 颜色 | light orange to dark orange |
| 溶解性 | DMSO: 5 mg/mL (clear solution) |
| 储存温度 | 2-8℃ |
| SMILES string | CCC(=O)NC(c1cccs1)c2cc([N+]([O-])=O)c3cccnc3c2O |
| InChI | 1S/C17H15N3O4S/c1-2-14(21)19-15(13-6-4-8-25-13)11-9-12(20(23)24)10-5-3-7-18-16(10)17(11)22/h3-9,15,22H,2H2,1H3,(H,19,21) |
| InChI key | DEXNORPUTBBNSC-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H319 |
| 预防措施声明 | P301 + P312 + P330 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
