NCTT-956

产品名称：

438575-88-3
NCTT-956
N-[(8-Hydroxy-5-nitro-7-quinolinyl)-2-thienylmethyl]-propanamide

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

NCTT-956 is a very potent, specific inhibitor of 12-lipoxygenase (12-LO) activity, with an IC₅₀ of 800 nM, no activity against 5-LO and greater than 25-fold selectivity over 15-LO. Specific inhibition of 12-LO by NCTT-956 in platelets blocks PKC activation, aggregation, granule secretion and αIIbB3 activation.

基本信息

经验(实验)分子式	C₁₇H₁₅N₃O₄S
分子量	357.38
MDL编号	MFCD02228855
PubChem化学物质编号	329825448

产品性质

质量水平	100
测定	≥97% (NMR)
形式	powder
颜色	light orange to dark orange
溶解性	DMSO: 5 mg/mL (clear solution)
储存温度	2-8℃
SMILES string	CCC(=O)NC(c1cccs1)c2cc([N+]([O-])=O)c3cccnc3c2O
InChI	1S/C17H15N3O4S/c1-2-14(21)19-15(13-6-4-8-25-13)11-9-12(20(23)24)10-5-3-7-18-16(10)17(11)22/h3-9,15,22H,2H2,1H3,(H,19,21)
InChI key	DEXNORPUTBBNSC-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H319
预防措施声明	P301 + P312 + P330 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable