ENMD-1068 盐酸盐

产品名称：

789488-77-3
ENMD-1068 hydrochloride
6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride
ENMD-1068 盐酸盐

产品介绍：

产品说明

应用

ENMD-1068 hydrochloride has been used as a protease-activated receptor 2 (PAR2) antagonist to determine the pathway responsible for paw edema induced by Crotalus durissus terrificus venom serine protease (Cdtsp 2).

包装

5, 25 mg in glass bottle

生化/生理作用

ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2). The compound blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice.
ENMD-1068 hydrochloride exhibits anti-angiogenic and anti-inflammatory activities.

基本信息

经验(实验)分子式	C₁₅H₂₉N₃O₂ · HCl
分子量	319.87
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 25 mg/mL, clear
储存温度	2-8℃

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable